If many SSRIs and SNRIs where failures in your treatment the SJW supplements will in all likelihood prove useless there. The main SJW mechanism as i'm sure you already know that the supplement world covets is monoamine reuptake inhibition, and it comes nowhere close to potency of the medications in clinical use. Won't hurt to try i just would advise to set expectations accordingly.

Hypericin and hyperforin are some of the active phytochemicals in SJW relevant to its MMOA, but they differ in specific bioeffects, e.g. hypericin is the main driver of SJW's possible yet not fully investigated phototoxicity concerns while hyperforin is what's most responsible for the altering of the major drug metabolizing liver enzymes...